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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg SPAAC is copper-free

SKU: 40463992479

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Description

SPAAC is copper-free

354 SMILES OCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

67 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO

Product Name: 5(6)-TAMRA azide Synonyms: 5-(and -6)-Carboxytetramethylrhodamine Azide CAS Number: N/A Molecular Formula: C28H28N6O4 Molecular Weight: 512

Product Name Pomalidomide-C2-OH Synonyms Pomalidomide-4'-C2-OH CAS Number 1957235-61-8 Related CAS Molecular Formula C15H15N3O5 Molecular Weight 317

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg SPAAC is copper-freeSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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